Article Summary
The President’s Emergency Plan for AIDS Relief (PEPFAR) is a significant U.S. commitment to addressing the global HIV/AIDS crisis. Established in 2003, PEPFAR is the largest commitment by any nation to address a single disease, providing HIV prevention and treatment services to millions worldwide. Over $120 billion has been committed to PEPFAR to date, with funding growing from $1.9 billion in FY 2004 to $6.5 billion in FY 2025. PEPFAR is a permanent part of U.S. law and has been reauthorized four times, with the most recent reauthorization in March 2024. However, PEPFAR is facing significant challenges due to the Trump administration’s review of all foreign assistance and a funding freeze, resulting in significant disruption and limitation of its scope and services.
What This Means for You
- Understand the importance of global health initiatives like PEPFAR and their impact on individual lives and global health outcomes.
- Stay informed about potential changes to PEPFAR and their implications for HIV prevention and treatment efforts worldwide.
- Advocate for continued support for PEPFAR and other global health programs to ensure sustained progress in addressing the HIV/AIDS crisis.
- Monitor the current review of foreign assistance by the Trump administration and its potential impact on global health programs.
Original Post
Note: This fact sheet largely reflects activities prior to the second Trump administration, which has issued numerous executive actions that directly affect global health efforts, and has been updated to highlight key recent actions that may affect PEPFAR. See also the KFF fact sheet on the Trump administration’s foreign aid review and the status of PEPFAR.
Key Facts
- PEPFAR has saved an estimated 26 million lives and provides HIV prevention and treatment services to millions.
- PEPFAR is the largest commitment by any nation to address a single disease, credited with changing the trajectory of the global HIV epidemic.
- PEPFAR funding is comprised of U.S. bilateral funding and U.S. contributions to multilateral organizations addressing HIV, primarily the Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund).
- Total PEPFAR funding has reached over $120 billion, growing from $1.9 billion in FY 2004 to $6.5 billion in FY 2025.
- PEPFAR is a permanent part of U.S. law and continues as long as Congress appropriates funding for the program, despite recent challenges and changes.
Key Terms
- PEPFAR
- Global Health
- HIV/AIDS
- Bilateral Funding
- Multilateral Funding
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